Role of S-nitrosylation in apoptosis resistance and carcinogenesis.

Abstract

Nitric oxide (NO) has been widely recognized as a positive regulator of tumorigenesis and cancer progression through its ability to regulate important proteins in various signal transduction pathways. S-Nitrosylation, or covalent attachment of NO to protein sulphydryl groups, has gained prominence as an important mechanism by which NO modulates physiologic… (More)
DOI: 10.1016/j.niox.2008.04.019

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