Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing.

@article{Hltje2005RoleOR,
  title={Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing.},
  author={Markus H{\"o}ltje and Anja Hoffmann and Fred Hofmann and Christian Mucke and Gisela Grosse and Nico Van Rooijen and Helmut Kettenmann and Ingo Just and Gudrun Ahnert-Hilger},
  journal={Journal of neurochemistry},
  year={2005},
  volume={95 5},
  pages={
          1237-48
        }
}
  • Markus Höltje, Anja Hoffmann, +6 authors Gudrun Ahnert-Hilger
  • Published in Journal of neurochemistry 2005
  • Medicine, Biology
  • Small Rho GTPases are key regulators of the cytoskeleton in a great variety of cells. Rho function mediates morphological changes as well as locomotor activity. Using astrocyte cultures established from neonatal mice we investigated the role of Rho in process formation during astrocyte stellation. Using a scratch-wound model, we examined the impact of Rho on a variety of morphological and functional variables such as stellation and migratory activity during wound healing. C3 proteins are widely… CONTINUE READING

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