Role of Rel/NF-kappaB transcription factors in apoptosis of human hepatocellular carcinoma cells.


BACKGROUND Primary hepatocellular carcinoma (HCC) is one of the 10 most common human carcinomas in the world. The mechanism by which HCC cells resist apoptosis induced by various treatment modalities is poorly understood. METHODS The authors sought to determine whether Rel/NF-kappaB transcription factors play a key role in controlling apoptosis in human… (More)


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