Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair.

@article{Symington2002RoleOR,
  title={Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair.},
  author={Lorraine S Symington},
  journal={Microbiology and molecular biology reviews : MMBR},
  year={2002},
  volume={66 4},
  pages={
          630-70, table of contents
        }
}
The process of homologous recombination is a major DNA repair pathway that operates on DNA double-strand breaks, and possibly other kinds of DNA lesions, to promote error-free repair. Central to the process of homologous recombination are the RAD52 group genes (RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2), most of which were identified by their requirement for the repair of ionizing-radiation-induced DNA damage in Saccharomyces cerevisiae. The Rad52 group… CONTINUE READING

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