Role of Platelet count as important prognostic marker in Pregnancy Induced Hypertension

  title={Role of Platelet count as important prognostic marker in Pregnancy Induced Hypertension},
  author={Dr. M. A. Sameer and Dr.D.P. Meshram and Dr.S.A. Deshpande and Dr.D. Sadhu and S Dr.Pandit},
  journal={IOSR Journal of Dental and Medical Sciences},
Introduction: Pregnancy induced hypertension (PIH) includes gestational hypertension, pre eclampsia and eclampsia. It occurs in approximately 11-29% pregnancies in indian population. Amongst all the parameters platelet count is the most simple and cost effective method for prediction of PIH, way before the appearance of derangements in PT, APTT and TT values . The study soughts the importance of platelet count as the most consistent and reliable method in early detection of PIH cases. Materials… 
Study showed that platelet indices were important, simple, effortless and cost effective investigations which can be used for early recognition of preventable eclampsia complications.
Platelet and Coagulation Parameters in Pregnancy Induced Hypertension and Eclampsia – A Tertiary Hospital Based Study
Introduction: Pregnancy-induced hypertension (PIH) is defined as newly diagnosed hypertension that occurs in pregnancy after 20 weeks of gestation and disappears following delivery of the baby. The
Estimation of Platelet Count As A Prognostic Marker for Feto-Maternal Outcome in Preeclampsia & Eclampsia
Introduction: Preeclampsia and eclampsia contribute greatly to the maternal morbidity and mortality.Thrombocytopenia is the most common hematological abnormality of all that occur in preeclampsia,
A comparison of platelet count in severe preeclampsia, mild preeclampsia and normal pregnancy
The frequency of thrombocytopenia was found to be directly related with the severity of disease, so platelet count can be used as a simple and cost effective tool to monitor the progression of preeclampsia, thereby preventing complications to develop during the gestational period.
Thrombocytopenia in hypertensive disorders of pregnancy
The incidence and severity of thrombocytopenia along with maternal and foetal complications encountered in the five groups were analysed and hypertensive disorders of pregnancy is recognized as a major cause of gestational throm bocy topenia.
Thrombocytopenia in Pregnancy Induced Hypertension
Platelet count alone cannot be relied upon to assess the severity of PIH and the search for a simple cost effective test for prompt management and prevention of maternal and neonatal morbidity performable in a rural hospital set up still continues.
Role of Platelet Distribution Width (PDW) and Plateletcrit in the Assessment of Nonthrombocytopenic Preeclampsia and Eclampsia
  • A. Singh, R. Varma
  • Medicine
    The Journal of Obstetrics and Gynecology of India
  • 2017
Platelet indices showed a significant variation along with the severity of the disease, which means these two platelet indices can become the new marker for an adverse outcome in preeclampsia and eClampsia even in women presenting with normal platelet counts.
A pattern of platelet indices as a potential marker for prediction of pre-eclampsia among pregnant women attending a Tertiary Hospital, Ethiopia: A case-control study
Platelet indices, including platelet count, mean platelet volume, platelet distribution width, and Platelet crit, have been identified as promising candidate markers for predicting preeclampsia in pregnant women.


Platelet estimation: its prognostic value in pregnancy induced hypertension.
The method of platelet estimation, not platelet count as an alternate procedure to estimate the degree of thrombocytopenia in patients with PIH cases indicated that there is an inverse relationship between the severity of PIH and platelet numbers.
Study of coagulation profile in pregnancy induced hypertension (PIH)
Raised aPTT and D-dimer are fairly good indicator of severe preeclampsia and needs aggressive treatment, according to a 2 year study on 100 PIH cases.
Characteristic Laboratory Changes in Pregnancies Complicated by HELLP Syndrome
It is found that the platelet count, LDH, AST, and total bilirubin levels proved to be useful indicators of the progression of HELLP syndrome.
Pregnancy induced hypertension and antithrombin-III.
There is evidence of consumption coagulopathy in PIH patients and AT-III activity shows a gradual and almost linear reduction in various groups ranging from normal pregnant women to eclampsia, which can be a useful marker for severity of PIH.
Coagulation Profile in Severe Preeclampsia
Whether a normal platelet count assures that no other clinically significant clotting abnormalities are present, and what level of thrombocytopenia predicts a risk of abnormalities in other coagulation indices are sought.
A prospective study investigating the mechanism of thrombocytopenia in preeclampsia.
It is indicated that, at least in nulliparous patients, thrombin action is not a major contributor to the development of thrombocytopenia in preeclampsia, and the observation of elevated levels of platelet-associated IgG suggests that immune mechanisms could contribute to the throm bocytopania in some patients.
Maternal and Perinatal Outcome in Severe Pre-eclampsia and Eclampsia
There is a very high maternal and perinatal morbidity and mortality and 82% patients had no antenatal care and it is suggested that developing countries have to go a long way to create awareness about importance of antenatal check ups and take measures for implementation.
Coagulation changes in eclampsia: their frequency and pathogenesis.
It is concluded that the coagulation changes when present in eclampsia are effect rather than cause and may evolve primarily from platelet adherence at sites of vascular endothelial damage as the consequence of segmental vasospasm and vasodilatation.
Combination Of Platelet & Uric Acid Estimation Can Predict Severity Of Pih Better
Individual predictive tests for Pregnancy Induced Hypertension (PIH) are yet to be reliable, valid, and economical. Therefore a combination of tests like platelet count & uric acid estimation was
Hemostatic Function in Healthy Pregnant and Preeclamptic Women: An Assessment Using the Platelet Function Analyzer (PFA-100®) and Thromboelastograph®
Impaired primary hemostatic function with increasing severity of preeclampsia was recorded by the PFA-100 but not the Thromboelastograph, a point-of-care platelet function analyzer.