Role of Piperine as an Effective Bioenhancer in Drug Absorption

  title={Role of Piperine as an Effective Bioenhancer in Drug Absorption},
  author={Mhaske Db and Sunil P. Sreedharan and Mahadik Kr},
  journal={Pharmaceutica Analytica Acta},
Bioenhancers can be defined as chemical entities, which when mixed with drugs promote and augment their bioavailability without showing any synergistic effect with the drug. The factors like toxicity, cost, poor bioavailability and long term administration of drugs give rise to the need of bioenhancers which help overcome most of these problems. Piper species produce a pungent alkaloid named Piperine or 1-peperoyl piperidine. Piperine increases permeability at the site of absorption by… 

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