Role of Piperine as an Effective Bioenhancer in Drug Absorption
@article{Db2018RoleOP, title={Role of Piperine as an Effective Bioenhancer in Drug Absorption}, author={Mhaske Db and S. Sreedharan and Mahadik Kr}, journal={Pharmaceutica Analytica Acta}, year={2018}, volume={09}, pages={1-4} }
Bioenhancers can be defined as chemical entities, which when mixed with drugs promote and augment their bioavailability without showing any synergistic effect with the drug. The factors like toxicity, cost, poor bioavailability and long term administration of drugs give rise to the need of bioenhancers which help overcome most of these problems. Piper species produce a pungent alkaloid named Piperine or 1-peperoyl piperidine. Piperine increases permeability at the site of absorption by… Expand
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References
SHOWING 1-10 OF 55 REFERENCES
Piperine-mediated drug interactions and formulation strategy for piperine: recent advances and future perspectives
- Chemistry, Medicine
- Expert opinion on drug metabolism & toxicology
- 2018
- 26
Effect of piperine on the bioavailability and pharmacokinetics of emodin in rats.
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 2015
- 42
Permeability characteristics of piperine on oral absorption--an active alkaloid from peppers and a bioavailability enhancer.
- Biology, Medicine
- Indian journal of experimental biology
- 1998
- 78
Investigation of Need of Natural Bioenhancer for a Metabolism Susceptible Drug—Raloxifene, in a Designed Self-Emulsifying Drug Delivery System
- Medicine, Chemistry
- AAPS PharmSciTech
- 2017
- 4
Enhancing the bioavailability of resveratrol by combining it with piperine.
- Chemistry, Medicine
- Molecular nutrition & food research
- 2011
- 215
- PDF
Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism.
- Chemistry, Medicine
- The Journal of pharmacology and experimental therapeutics
- 1985
- 310
Influence of Co-Administration of Piperine on Pharmacokinetic Profile of Gatifloxacin in Layer Birds
- Chemistry
- 2011
- 10
- PDF
Enhancement of oral bioavailability and immune response of Ginsenoside Rh2 by co-administration with piperine.
- Chemistry, Medicine
- Chinese journal of natural medicines
- 2018
- 10
- PDF
Influence of piperine on ibuprofen induced antinociception and its pharmacokinetics.
- Chemistry, Medicine
- Arzneimittel-Forschung
- 2011
- 17