Role of PTEN and MMP-7 expression in growth, invasion, metastasis and angiogenesis of gastric carcinoma.

@article{Zheng2003RoleOP,
  title={Role of PTEN and MMP-7 expression in growth, invasion, metastasis and angiogenesis of gastric carcinoma.},
  author={Hua-Chuan Zheng and Jin-min Sun and Xiao-han Li and Xuefei Yang and Yin-chang Zhang and Yan Tao Xin},
  journal={Pathology international},
  year={2003},
  volume={53 10},
  pages={659-66}
}
To investigate the role of PTEN and matrix metalloproteinase-7 (MMP-7) expression in tumorigenesis and progression of gastric carcinoma, their expression in 113 gastric carcinomas was studied by immunohistochemistry. Microvessel density (MVD) was counted using the anti-CD34 antibody. The expressions of PTEN and MMP-7, and MVD were compared with the clinicopathological parameters of tumors, and the relationship between PTEN and MMP-7 expression and MVD was analyzed. It was found that PTEN was… CONTINUE READING

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