Role of PKC-β in chemical allergen-induced CD86 expression and IL-8 release in THP-1 cells

@article{Corsini2013RoleOP,
  title={Role of PKC-β in chemical allergen-induced CD86 expression and IL-8 release in THP-1 cells},
  author={Emanuela Corsini and Valentina Galbiati and Philipp R Esser and Antonella Pinto and Marco Racchi and Marina Marinovich and Stefan F Martin and Corrado Lodovico Galli},
  journal={Archives of Toxicology},
  year={2013},
  volume={88},
  pages={415-424}
}
We previously demonstrated an age-related decrease in receptor for activated C-kinase (RACK-1) expression and functional deficit in Langerhans cells’ responsiveness. This defect specifically involves the translocation of protein kinase C (PKC)-β. The purpose of this study was to investigate the role of RACK-1 and PKC-β in chemical allergen-induced CD86… CONTINUE READING