Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy

Abstract

The superfamily of organic anion-transporting polypeptides (OATPs, gene symbol SLCO) includes important transporters handling a variety of endogenous and xenobiotic substrates. Currently, 11 human OATPs are known and their substrates include endogenous hormones and their conjugates, anticancer drugs, and imaging agents. The contribution of OATPs to the in… (More)
DOI: 10.1208/s12248-015-9740-x

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