Role of Nitric Oxide in the Hypoxemia-Induced Renal Dysfunction of the Newborn Rabbit

@article{Ballvre1996RoleON,
  title={Role of Nitric Oxide in the Hypoxemia-Induced Renal Dysfunction of the Newborn Rabbit},
  author={Laurence D. Ball{\`e}vre and Michael Larry Thonney and Jean-pierre Guignard},
  journal={Pediatric Research},
  year={1996},
  volume={39},
  pages={725-730}
}
The current study was performed in 30 anesthetized and mechanically ventilated newborn rabbits to investigate the role of the endothelium-derived relaxing factor nitric oxide (NO) in the renal vasoconstriction observed during hypoxemia. Renal blood flow (RBF) and GFR were determined by the clearance of p-aminohippuric acid and inulin, respectively. In nine newborn rabbits (group 1), acute hypoxemia induced a significant decrease in RBF (-17 ± 7%) and GFR (-11 ± 6%). A second group of nine… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Glomerular and tubular responses to N(G)-nitro-L-arginine methyl ester are age dependent in conscious lambs.

American journal of physiology. Regulatory, integrative and comparative physiology • 2002
View 1 Excerpt

Effect of severe normocapnic hypoxia on renal function in growth-restricted newborn piglets.

American journal of physiology. Regulatory, integrative and comparative physiology • 2000
View 3 Excerpts

L-arginine reduces tubular cell injury in acute post-ischaemic renal failure.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association • 1999

Similar Papers

Loading similar papers…