• Biology
  • Published 2010

Role of Neurokinin 1 Receptor in Modulating the Immune-Stimulatory Function of Dendritic Cells

@inproceedings{Janelsins2010RoleON,
  title={Role of Neurokinin 1 Receptor in Modulating the Immune-Stimulatory Function of Dendritic Cells},
  author={Brian M. Janelsins},
  year={2010}
}
There is a growing body of evidence indicating that the nervous and immune systems cross-talk during inflammatory and immune responses. Secretion of pro-inflammatory neuropeptides from the tachykinin family, including substance P (SP) and hemokinin-1 (HK-1), favors cellular immunity by binding the neurokinin 1 receptor (NK1R) to promote immune cell survival and activation. Dendritic cells (DCs) are essential for the stimulation of cellular immunity; however, the ability of pro-inflammatory… CONTINUE READING

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