Role of NOD2 variants in spondylarthritis.


OBJECTIVE To investigate the role of the gene NOD2 in susceptibility to, and clinical manifestations of, ankylosing spondylitis (AS). METHODS A case-control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro(268)Ser, Arg(702)Trp, Gly(908)Arg, and Leu(1007)fsinsC) was performed in 229 cases of primary AS with no diagnosed… (More)


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@article{Crane2002RoleON, title={Role of NOD2 variants in spondylarthritis.}, author={Alison M. Crane and Linda A. Bradbury and David A van Heel and Dermot P. B. McGovern and Sinead Brophy and Laurence A. Rubin and Katherine Anne Siminovitch and Bryan Paul Wordsworth and Andrei Calin and Matt Brown}, journal={Arthritis and rheumatism}, year={2002}, volume={46 6}, pages={1629-33} }