Role of NCAM, cadherins, and microfilaments in cell-cell contact formation in TM4 immature mouse sertoli cells.

@article{Sandig1997RoleON,
  title={Role of NCAM, cadherins, and microfilaments in cell-cell contact formation in TM4 immature mouse sertoli cells.},
  author={Martin Sandig and Vitauts I. Kalnins and C. H. Siu},
  journal={Cell motility and the cytoskeleton},
  year={1997},
  volume={36 2},
  pages={
          149-63
        }
}
To determine events that lead to the formation of intercellular contacts, we examined the spatial and temporal distribution of NCAM, cadherins, and F-actin in TM4 cells by immunofluorescence and laser scanning confocal microscopy. TM4 cells exhibited epithelioid characteristics and formed large overlapping lamella-like cell-cell contacts that contained a high concentration of NCAM. NCAM-rich lamellae formed from smaller NCAM patches at the ends of filopodia-like contacts between adjacent cells… CONTINUE READING