Role of NADPH oxidase-derived superoxide in reduced size liver ischemia and reperfusion injury.

@article{Harada2004RoleON,
  title={Role of NADPH oxidase-derived superoxide in reduced size liver ischemia and reperfusion injury.},
  author={Hirohisa Harada and Ian Neil Hines and Sonia Flores and Bifeng Gao and J M Mccord and Helen Scheerens and Matthew B Grisham},
  journal={Archives of biochemistry and biophysics},
  year={2004},
  volume={423 1},
  pages={103-8}
}
Hepatic resection with concomitant periods of ischemia and reperfusion (I/R) is required to perform reduced size liver transplantation such as split liver or liver donor transplantation. Although great progress has been made using these types of surgeries, there remains substantial risk to both donors and recipients, with a significant number of patients developing liver injury and failure. The objective of this study was to assess the roles of superoxide (O(2)(-)) and tumor necrosis factor… CONTINUE READING

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