Role of MyD88 in TLR agonist-induced functional alterations of human adipose tissue-derived mesenchymal stem cells

@article{Yu2008RoleOM,
  title={Role of MyD88 in TLR agonist-induced functional alterations of human adipose tissue-derived mesenchymal stem cells},
  author={Sungsook Yu and Hyun Hwa Cho and Hye Joon Joo and Yong Chan Bae and Jin Sup Jung},
  journal={Molecular and Cellular Biochemistry},
  year={2008},
  volume={317},
  pages={143-150}
}
Toll-like receptors (TLRs) sense microorganism components and are critical host mediators of inflammation during infection. Recently, TLRs have been reported to be involved in cell proliferation and differentiation. We previously reported that TLR agonists might affect proliferation and differentiation of human adipose tissue-derived mesenchymal stem cells (hASCs). In this study, we sought to determine whether TLR signaling is dependent on MyD88 in hASCs. The hASCs were downregulated using LV… CONTINUE READING
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