Role of My Cooperation with Soviet Scientists in the Elimination of Polio: Possible Lessons for Relations between the U.S.A. and the USSR

@article{Sabin1987RoleOM,
  title={Role of My Cooperation with Soviet Scientists in the Elimination of Polio: Possible Lessons for Relations between the U.S.A. and the USSR},
  author={A. Sabin},
  journal={Perspectives in Biology and Medicine},
  year={1987},
  volume={31},
  pages={57 - 64}
}
  • A. Sabin
  • Published 1987
  • Medicine
  • Perspectives in Biology and Medicine
The purpose of this communication is threefold: (1) to bring into perspective the important role ofmy cooperation with Soviet scientists in the development of the oral poliovirus vaccine used for more than 25 years for the elimination of paralytic poliomyelitis; (2) to describe the obstacles to worldwide eradication of the disease; and (3) to describe a hope I have derived from this experience that cooperative endeavors between the U.S.A. and the Soviet Union against the larger common enemy of… Expand
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TLDR
The main challenge in the present era is the economically undeveloped tropical and subtropical regions with inadequate health services that are inhabited by more than half of the world population, where recent surveys for residual paralysis due to poliomyelitis have shown that the incidence of the disease has been higher than it was in the USA and other predominantly temperate-climate countries before the vaccine era. Expand
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  • Medicine
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TLDR
A new strategy--namely, bringing the vaccine to the people during annual national days of vaccination--has already been used successfully in some small and large developing countries of Latin America for the rapid elimination of polio and could be adapted to include vaccination against measles, pertussis, and neonatal tetanus. Expand
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TLDR
Information is brought up to date on four topics that came under special consideration in the recent discussions of vaccination against poliomyelitis, including neurotropism of viruses excreted by the vaccinated individuals and after further multiplication in contacts. Expand
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TLDR
Experience in Cuba, Brazil, and in the Dominican Republic has shown that the strategy of annual short-term vaccination of all children in the most susceptible age groups can rapidly eliminate the disease from tropical and subtropical countries. Expand
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TLDR
Oral poliovirus vaccine has eliminated paralytic poliomyelitis caused by polioviruses in many temperate-climate countries in which a large proportion of children remain unvaccinated or incompletely vaccinated. Expand
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It is shown that the killed virus vaccine has greatly reduced the incidence of paralytic poliomyelitis wherever it has been used extensively and has the following properties of special importance for the complete elimination or eradication of the disease. Expand
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More precise and comparable data about the risk of poliomyelitis could be obtained in future surveys by incorporating a standard case definition, using house-to-house case-finding methods in representative community-based samples, analyzing and presenting rates in more clearly defined ways, and by selecting stable populations for study. Expand
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