Role of Mobile DNA in the Evolution of Vancomycin-Resistant Enterococcus faecalis

@article{Paulsen2003RoleOM,
  title={Role of Mobile DNA in the Evolution of Vancomycin-Resistant Enterococcus faecalis},
  author={I. Paulsen and L. Banerjei and G. Myers and K. Nelson and R. Seshadri and T. Read and D. Fouts and J. Eisen and S. Gill and J. Heidelberg and H. Tettelin and R. Dodson and L. Umayam and L. Brinkac and M. Beanan and S. Daugherty and R. Deboy and S. Durkin and J. Kolonay and R. Madupu and W. Nelson and J. Vamathevan and B. Tran and J. Upton and T. Hansen and J. Shetty and H. Khouri and T. Utterback and D. Radune and K. Ketchum and B. Dougherty and C. Fraser},
  journal={Science},
  year={2003},
  volume={299},
  pages={2071 - 2074}
}
Key ResultThe complete genome sequence of Enterococcus faecalis V583, a vancomycin-resistant clinical isolate, revealed that more than a quarter of the genome consists of probable mobile or foreign DNA. One of the predicted mobile elements is a previously unknown vanB vancomycin-resistance conjugative transposon. Three plasmids were identified, including two pheromone-sensing conjugative plasmids, one encoding a previously undescribed pheromone inhibitor. The apparent propensity for the incorporation of…Expand
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5
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References

SHOWING 1-10 OF 43 REFERENCES
In vitro susceptibility studies of vancomycin-resistant Enterococcus faecalis.
...
1
2
3
4
5
...