Role of Mitochondria in Parvovirus Pathology

  title={Role of Mitochondria in Parvovirus Pathology},
  author={Jonna Nykky and Matti Vuento and L Gilbert},
  booktitle={PloS one},
Proper functioning of the mitochondria is crucial for the survival of the cell. Viruses are able to interfere with mitochondrial functions as they infect the host cell. Parvoviruses are known to induce apoptosis in infected cells, but the role of the mitochondria in parvovirus induced cytopathy is only partially known. Here we demonstrate with confocal and electron microscopy that canine parvovirus (CPV) associated with the mitochondrial outer membrane from the onset of infection. During viral… CONTINUE READING


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Apoptosis induced by NS 1 gene of Canine Parvovirus2 is caspase dependent and p 53 independent

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