Role of Mitochondria and Endoplasmic Reticulum in Taurine-Deficiency-Mediated Apoptosis

@inproceedings{Jong2017RoleOM,
  title={Role of Mitochondria and Endoplasmic Reticulum in Taurine-Deficiency-Mediated Apoptosis},
  author={Chian Ju Jong and Takashi Ito and Howard Prentice and Jang-Yen Wu and Stephen W. Schaffer},
  booktitle={Nutrients},
  year={2017}
}
Taurine is a ubiquitous sulfur-containing amino acid found in high concentration in most tissues. Because of its involvement in fundamental physiological functions, such as regulating respiratory chain activity, modulating cation transport, controlling inflammation, altering protein phosphorylation and prolonging lifespan, taurine is an important nutrient whose deficiency leads to severe pathology and cell death. However, the mechanism by which taurine deficiency causes cell death is… CONTINUE READING