Role of Microexudate Carpet in Cell Division

@article{Yaoi1972RoleOM,
  title={Role of Microexudate Carpet in Cell Division},
  author={Yoshihito Yaoi and Toku Kanaseki},
  journal={Nature},
  year={1972},
  volume={237},
  pages={283-285}
}
THE growth rate of cells isolated from higher organisms depends largely on population density. At low cell densities, cells have a low probability of growing in usual culture conditions (reviewed in ref. 1). Cell growth can be sustained in sparse cultures using X-irradiated feeder layers or conditioned medium. Feeder layers are thought to enhance growth by producing “conditioned factor”, which seems to be restricted to the vicinity of feeder cells2–4, and is hardly diffusible into culture… CONTINUE READING