Role of Microbiota and Innate Immunity in Recurrent Clostridium difficile Infection

@inproceedings{Bibb2014RoleOM,
  title={Role of Microbiota and Innate Immunity in Recurrent Clostridium difficile Infection},
  author={Stefano Bibb{\`o} and Loris Riccardo Lopetuso and Gianluca Ianiro and Teresa Antonella Di Rienzo and Antonio Gasbarrini and Giovanni Cammarota},
  booktitle={Journal of immunology research},
  year={2014}
}
Recurrent Clostridium difficile infection represents a burdensome clinical issue whose epidemiology is increasing worldwide. The pathogenesis is not yet completely known. Recent observations suggest that the alteration of the intestinal microbiota and impaired innate immunity may play a leading role in the development of recurrent infection. Various factors can cause dysbiosis. The causes most involved in the process are antibiotics, NSAIDs, acid suppressing therapies, and age. Gut microbiota… CONTINUE READING