Role of Lactobacillus in the Prevention of Antibiotic‐Associated Diarrhea: A Meta‐analysis

@article{KalePradhan2010RoleOL,
  title={Role of Lactobacillus in the Prevention of Antibiotic‐Associated Diarrhea: A Meta‐analysis},
  author={Pramodini B. Kale-Pradhan and Harjot K. Jassaly and Sheila M. Wilhelm},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  year={2010},
  volume={30}
}
STUDY OBJECTIVE To evaluate the efficacy of a Lactobacillus probiotic single-agent regimen in preventing antibiotic-associated diarrhea (AAD. [] Key Method Patients. A total of 1862 pediatric and adult patients who received a Lactobacillus single-agent regimen or placebo for the prevention of AAD.

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The results from 22/23 trials reporting on the incidence of diarrhea show a precise benefit from probiotics compared to active, placebo or no treatment control, and this benefit remained statistically significant in an extreme plausible situation.
...

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