Role of Lactobacillus in the Prevention of Antibiotic‐Associated Diarrhea: A Meta‐analysis

@article{KalePradhan2010RoleOL,
  title={Role of Lactobacillus in the Prevention of Antibiotic‐Associated Diarrhea: A Meta‐analysis},
  author={Pramodini B. Kale-Pradhan and Harjot K. Jassaly and Sheila M. Wilhelm},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  year={2010},
  volume={30}
}
STUDY OBJECTIVE To evaluate the efficacy of a Lactobacillus probiotic single-agent regimen in preventing antibiotic-associated diarrhea (AAD. [] Key Method Patients. A total of 1862 pediatric and adult patients who received a Lactobacillus single-agent regimen or placebo for the prevention of AAD.
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The Use of Probiotics to Prevent Antibiotic Associated Diarrhea: Current Primary Care Practice and Introduction of an Evidence Based Practice Protocol

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TLDR
Results from 33 trials reporting on the incidence of diarrhea show a precise benefit from probiotics compared to active, placebo or no treatment control, and heterogeneity indicated that high dose is more effective than low probiotic dose.

EFECTOS CLÍNICOS DE LOS PROBIÓTICOS: QUÉ DICE LA EVIDENCIA CLINICAL EFECTS OF PROBIOTICS: WHAT DOES THE EVIDENCE SAYS

TLDR
A summary of the scientific evidence supporting the principal biological effects of the probiotics in digestive function, immune response, andlipid profile, relevant in the functional food development is presented.

Efficacy of the Probiotic Probiotical Confirmed in Acute Gastroenteritis

TLDR
The test product was shown to normalize stool consistency significantly more rapidly than the placebo, and these data confirm the findings from a previous study in a larger group of children performed in a primary healthcare setting.

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TLDR
Although the Lacidofil® cap does not reduce the rate of occurrence of AAD in adult patients with respiratory tract infection who have taken antibiotics, the Lactobacillus group maintains their bowel habits to a greater extent than the placebo group.

Probiotics for the prevention of pediatric antibiotic-associated diarrhea.

TLDR
The results from 22/23 trials reporting on the incidence of diarrhea show a precise benefit from probiotics compared to active, placebo or no treatment control, and this benefit remained statistically significant in an extreme plausible situation.
...

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