Role of La Crosse virus glycoproteins in attachment of virus to host cells.

@article{Ludwig1991RoleOL,
  title={Role of La Crosse virus glycoproteins in attachment of virus to host cells.},
  author={George V. Ludwig and Babara A Israel and Bruce M. Christensen and T M Yuill and Kathryn Schultz},
  journal={Virology},
  year={1991},
  volume={181 2},
  pages={564-71}
}
Data presented in this report demonstrate that the initial event of La Crosse virus (LACV) infection of cells is probably the interaction of viral glycoproteins with specific cellular receptor sites. We have shown that LACV glycoprotein G1 binds, in a dose-dependent manner, to continuous vertebrate and mosquito cell lines, but not to mosquito midguts isolated ex vivo. This binding can be inhibited by the pretreatment of cells with excess homologous glycoprotein but not with excess heterologous… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

Similar Papers

Loading similar papers…