Role of Kv1 Potassium Channels in Regulating Dopamine Release and Presynaptic D2 Receptor Function

@inproceedings{Martel2011RoleOK,
  title={Role of Kv1 Potassium Channels in Regulating Dopamine Release and Presynaptic D2 Receptor Function},
  author={Philippe Martel and Damiana Leo and Stephanie Fulton and Maxime B{\'e}rard and L. C. Trudeau},
  booktitle={PloS one},
  year={2011}
}
Dopamine (DA) release in the CNS is critical for motor control and motivated behaviors. Dysfunction of its regulation is thought to be implicated in drug abuse and in diseases such as schizophrenia and Parkinson's. Although various potassium channels located in the somatodendritic compartment of DA neurons such as G-protein-gated inward rectifying potassium channels (GIRK) have been shown to regulate cell firing and DA release, little is presently known about the role of potassium channels… CONTINUE READING
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