Role of KCNJ5 in familial and sporadic primary aldosteronism


Primary aldosteronism is characterised by the dysregulation of aldosterone production and comprises both sporadic forms, caused by an aldosterone-producing adenoma or bilateral adrenal hyperplasia, and familial forms (familial hyperaldosteronism types I, II and III). The two principal physiological regulators of aldosterone synthesis are angiotensin II and… (More)
DOI: 10.1038/nrendo.2012.230


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