Role of Integrin-linked kinase in extracellular matrix remodeling and cell fate decisions

@inproceedings{Morgner2014RoleOI,
  title={Role of Integrin-linked kinase in extracellular matrix remodeling and cell fate decisions},
  author={Jessica Morgner},
  year={2014}
}
The extracellular matrix (ECM) functions as a structural scaffold for tissues and regulates signaling by interacting with specific receptors and by providing a reservoir for growth factors. This multitude of functions makes the ECM an essential regulator of organ development and maintenance. The deposition and remodeling of the ECM into a precise configuration is a cell-dependent process that requires integrin adhesion receptors and the generation of cellular forces. However, it is not clear… CONTINUE READING

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