Corpus ID: 212476413

Role of Instability in the Action of Indole-3-carbinol (I3C)

@inproceedings{Bradlow2009RoleOI,
  title={Role of Instability in the Action of Indole-3-carbinol (I3C)},
  author={H. Bradlow},
  year={2009}
}
  • H. Bradlow
  • Published 2009
  • Assessment of the oral use of indole-3-carbinol (I3C) as a chemoprotective compound has not sufficiently considered the chemical instability of I3C. This review addresses the question of whether I3C is directly active in its own right or only serves as a precursor, with all of the biological responses coming from reaction products arising in culture media and in the presence of stomach acid. Because of the rapid conversion of I3C into its dimer. diindolylmethane (DIM), and trimers very little… CONTINUE READING

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