Role of Imidazoline‐preferring Receptors in the Genesis of Epinephrine‐induced Arrhythmias in Halothane‐anesthetized Dogs

@article{Hayashi1993RoleOI,
  title={Role of Imidazoline‐preferring Receptors in the Genesis of Epinephrine‐induced Arrhythmias in Halothane‐anesthetized Dogs},
  author={Y. Hayashi and T. Kamibayashi and M. Maze and A. Yamatodani and K. Sumikawa and M. Kuro and I. Yoshiya},
  journal={Anesthesiology},
  year={1993},
  volume={78},
  pages={524–530}
}
BackgroundDrugs with a central α2-adrenergic action can increase the threshold for halothane-eplnephrine-lnduced arrhythmias. Recently, imidazoline-preferrlng receptors were shown to play a significant role in the hypotensive effect of α2-adrenergic agonists containing an imidazole ring in their structure. To address the question of whether the antiar-rhythmic property of the α2-adrenergic agonists was caused by activation of α2-adrenoceptors or imldazoline-preferrlng receptors in the central… Expand
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