Role of IgM in human monocyte-mediated target cell destruction in vitro.


The presence on human monocytes of surface receptors binding IgM molecules (Fc mu receptors) and the role of IgM antibodies in monocytic effector functions were investigated. IgM antibodies were first purified by one passage through anti-Fc gamma immunosorbent. Rosette techniques in which either the indicator erythrocytes or the monocytes had been… (More)


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