Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation.

@article{Hbner2010RoleOH,
  title={Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation.},
  author={Michael R. H{\"u}bner and David L. Spector},
  journal={Cold Spring Harbor symposia on quantitative biology},
  year={2010},
  volume={75},
  pages={43-9}
}
The influence of histone amino-terminal covalent modifications on gene regulation has drawn intense research efforts in recent years. It is now clear that activating and inactivating modifications have a key role in determining the gene-expression profile of an individual cell or cell lineage. Thus, differences in these modifications have a pivotal role in determining and maintaining cell fate during development. The interplay of histone methyltransferases (HMTs) and demethylases confers the… CONTINUE READING

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Human LSD 2 / KDM 1 b / AOF 1 regulates gene transcription by modulating intragenic H 3 K 4 me 2 methylation

  • R Fang, AJ Barbera, +7 authors C Lian
  • Mol Cell
  • 2010

The Jmjd 3Irf 4 axis regulates M 2 macrophage polarization and host responses against helminth infection

  • T Satoh, O Takeuchi, +7 authors T Saitoh
  • Nat Immunol .
  • 2010

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