Role of H1 linker histones in mammalian development and stem cell differentiation.

Abstract

H1 linker histones are key chromatin architectural proteins facilitating the formation of higher order chromatin structures. The H1 family constitutes the most heterogeneous group of histone proteins, with eleven non-allelic H1 variants in mammals. H1 variants differ in their biochemical properties and exhibit significant sequence divergence from one… (More)
DOI: 10.1016/j.bbagrm.2015.12.002

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