Role of Genotype in the Cycle of Violence in Maltreated Children

@article{Caspi2002RoleOG,
  title={Role of Genotype in the Cycle of Violence in Maltreated Children},
  author={Avshalom Caspi and Joseph L. McClay and Terrie E. Moffitt and Jonathan S Mill and Judy L. Martin and Ian W. Craig and Alan H. Taylor and Richie Poulton},
  journal={Science},
  year={2002},
  volume={297},
  pages={851 - 854}
}
We studied a large sample of male children from birth to adulthood to determine why some children who are maltreated grow up to develop antisocial behavior, whereas others do not. A functional polymorphism in the gene encoding the neurotransmitter-metabolizing enzyme monoamine oxidase A (MAOA) was found to moderate the effect of maltreatment. Maltreated children with a genotype conferring high levels of MAOA expression were less likely to develop antisocial problems. These findings may partly… 

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...

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