Role of Gas6/Axl signaling in lens epithelial cell proliferation and survival.

@article{Valverde2004RoleOG,
  title={Role of Gas6/Axl signaling in lens epithelial cell proliferation and survival.},
  author={Paloma Valverde and Martin S. Obin and Allen Taylor},
  journal={Experimental eye research},
  year={2004},
  volume={78 1},
  pages={27-37}
}
Axl is a receptor tyrosine kinase that is activated by Gas6, a growth factor that belongs to the vitamin K-dependent protein family. Although Gas6 binding to Axl has been shown to transmit mitogenic and/or antiapoptotic signals to a variety of cell types, the role of the Axl-Gas6 system in normal and pathological lens biology is not known. We demonstrate… CONTINUE READING