Role of GPR30 in endometrial pathology after tamoxifen for breast cancer.

  title={Role of GPR30 in endometrial pathology after tamoxifen for breast cancer.},
  author={Tanja Ignatov and Holm Eggemann and Andrzej Semczuk and Bobbie J. Smith and Joachim Bischoff and Albert Roessner and Serban Dan Costa and Thomas Kalinski and Atanas Ignatov},
  journal={American journal of obstetrics and gynecology},
  volume={203 6},
OBJECTIVE This study was undertaken to evaluate the potential role of G-protein-coupled estrogen receptor in endometrial pathology associated with tamoxifen treatment of breast cancer patients. STUDY DESIGN We investigated whether G-protein-coupled estrogen receptor plays a role in mediating proliferating effect of tamoxifen in endometrial carcinoma cells. These results were compared with the G-protein-coupled estrogen receptor expression pattern in endometrial tissue from a cohort of 95… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 28 references

American rognostication and prediction in the postenomic era

  • R hrisanthar, Lillehaug
  • Ann Oncol
  • 2010

Role of GPR 30 in the mechaisms of tamoxifen resistance in breast cancer CF7 cells

  • A Ignatov, T Ignatov, A Roessner, D Costa, T Kalinski
  • Breast Cancer Res Treat
  • 2010

Stimu - ating the GPR 30 estrogen receptor with a novel amoxifen analogue activates SF1 and prootes endometrial cell proliferation

  • BC Lin, M SuzaWa, RD Blind
  • Cancer es
  • 2009

RANTES stimulates CA 2  moilization and inositol trisphosphate ( IP 3 ) foration in cells transfected with G proteinoupled receptor 75

  • A Ignatov, J Robert, C Gregory-Evans, HC challer
  • Br J Pharmacol
  • 2006

Effects of chemotherapy and ormonal therapy for early breast cancer on reurrence and 15 - year survival : an overview of he randomised trials

  • T Fornander, LE Rutqvist, B Cedermark
  • Lancet
  • 2005

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