Role of Frizzled6 in the molecular mechanism of beta-carotene action in the lung.

Abstract

β-Carotene (BC) is omnipresent in our diet, both as natural food component as well as an additive. BC and its metabolites have important biological functions. For this reason, BC is generally considered to be a health promoting compound. Two human trials, however, have described adverse effects in lung tissue, increasing the risk of lung cancer. We… (More)
DOI: 10.1016/j.tox.2014.03.002

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