Role of Fatty Acid Composition in the Development of Metabolic Disorders in Sucrose-Induced Obese Rats

  title={Role of Fatty Acid Composition in the Development of Metabolic Disorders in Sucrose-Induced Obese Rats},
  author={Satoshi Fukuchi and Kazuyuki Hamaguchi and Masataka Seike and Katsuro Himeno and Toshiie Sakata and Hironobu Yoshimatsu},
  journal={Experimental Biology and Medicine},
  pages={486 - 493}
Fatty acids have been shown to be involved in the development of insulin resistance associated with obesity. We used sucrose loading in rats to analyze changes in fatty acid composition in the progression of obesity and the related metabolic disorder. Although rats fed a sucrose diet for 4 weeks had body weights similar to those of control animals, their visceral fat pads were significantly larger, and serum triglyceride levels were higher; however, neither plasma glucose nor insulin levels… 

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