Role of FNR and FNR-regulated, sugar fermentation genes in Neisseria meningitidis infection.

@article{Bartolini2006RoleOF,
  title={Role of FNR and FNR-regulated, sugar fermentation genes in Neisseria meningitidis infection.},
  author={Erika Bartolini and Elisabetta Frigimelica and Serena Giovinazzi and Giuliano Galli and Yazdani B Shaik and Caroline A. Genco and Jo Anne Welsch and Dan M Granoff and Guido Grandi and Renata M. Grifantini},
  journal={Molecular microbiology},
  year={2006},
  volume={60 4},
  pages={963-72}
}
While it is generally accepted that anaerobic metabolism is required during infection, supporting experimental data have only been described in a limited number of studies. To provide additional evidence on the role of anaerobic metabolism in bacterial pathogens while invading mammalian hosts, we analysed the effect of the inactivation of FNR, the major regulatory protein involved in the adaptation to oxygen restrictive conditions, and of two of the FNR-regulated genes on the survival of… CONTINUE READING

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