Role of FAST Kinase Domains 3 (FASTKD3) in Post-transcriptional Regulation of Mitochondrial Gene Expression*

  title={Role of FAST Kinase Domains 3 (FASTKD3) in Post-transcriptional Regulation of Mitochondrial Gene Expression*},
  author={Erik Boehm and Mar{\'i}a Zornoza and Alexis A. Jourdain and Aitor Delmiro Magdalena and In{\'e}s Garc{\'i}a‐Consuegra and Rebeca Torres Merino and Antonio Ordu{\~n}a and Miguel {\'A}ngel Mart{\'i}n and Jean-Claude Martinou and Miguel Angel de la Fuente and Mar{\'i}a Simarro},
  journal={The Journal of Biological Chemistry},
  pages={25877 - 25887}
The Fas-activated serine/threonine kinase (FASTK) family of proteins has recently emerged as a central regulator of mitochondrial gene expression through the function of an unusual RNA-binding domain named RAP (for RNA-binding domain abundant in Apicomplexans), shared by all six members of the family. Here we describe the role of one of the less characterized members, FASTKD3, in mitochondrial RNA metabolism. First, we show that, in contrast to FASTK, FASTKD2, and FASTKD5, FASTKD3 does not… 

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