Role of Estrogens in the Regulation of Liver Lipid Metabolism.

  title={Role of Estrogens in the Regulation of Liver Lipid Metabolism.},
  author={Brian T. Palmisano and Lin Zhu and John M. Stafford},
  journal={Advances in experimental medicine and biology},
Before menopause, women are protected from atherosclerotic heart disease associated with obesity relative to men. Sex hormones have been proposed as a mechanism that differentiates this risk. In this review, we discuss the literature around how the endogenous sex hormones and hormone treatment approaches after menopause regulate fatty acid, triglyceride, and cholesterol metabolism to influence cardiovascular risk.The important regulatory functions of estrogen signaling pathways with regard to… CONTINUE READING