Role of EspF in host cell death induced by enteropathogenic Escherichia coli.

@article{Crane2001RoleOE,
  title={Role of EspF in host cell death induced by enteropathogenic Escherichia coli.},
  author={John K Crane and Basil McNamara and Michael S. Donnenberg},
  journal={Cellular microbiology},
  year={2001},
  volume={3 4},
  pages={197-211}
}
Enteropathogenic Escherichia coli (EPEC) causes diarrhoea in children in developing countries. Many EPEC genes involved in virulence are contained within the locus of enterocyte effacement (LEE), a large pathogenicity island. One of the genes at the far righthand end of the LEE encodes EspF, an EPEC secreted protein of unknown function. EspF, like the other Esps, is a substrate for secretion by the type III secretory system. Previous studies found that an espF mutant behaved as wild type in… CONTINUE READING