Role of Escherichia coli O157:H7 virulence factors in colonization at the bovine terminal rectal mucosa.

@article{Sheng2006RoleOE,
  title={Role of Escherichia coli O157:H7 virulence factors in colonization at the bovine terminal rectal mucosa.},
  author={Haiqing Q Sheng and Ji Youn Lim and Hannah J Knecht and Jie Li and Carolyn J. Hovde},
  journal={Infection and immunity},
  year={2006},
  volume={74 8},
  pages={
          4685-93
        }
}
The human pathogen Escherichia coli O157:H7 causes hemorrhagic colitis and life-threatening sequelae and transiently colonizes healthy cattle at the terminal rectal mucosa. This study analyzed virulence factors important for the clinical manifestations of human E. coli O157:H7 infection for their contribution to the persistence of E. coli in cattle. The colonizing ability of E. coli O157:H7 was compared with those of nonpathogenic E. coli K-12 and isogenic deletion mutants missing Shiga toxin… CONTINUE READING
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