Role of Energy Metabolism in the Brown Fat Gene Program

@inproceedings{Nam2015RoleOE,
  title={Role of Energy Metabolism in the Brown Fat Gene Program},
  author={Minwoo Nam and Marcus P. Cooper},
  booktitle={Front. Endocrinol.},
  year={2015}
}
In murine and human brown adipose tissue (BAT), mitochondria are powerful generators of heat that safely metabolize fat, a feature that has great promise in the fight against obesity and diabetes. Recent studies suggest that the actions of mitochondria extend beyond their conventional role as generators of heat. There is mounting evidence that impaired mitochondrial respiratory capacity is accompanied by attenuated expression of Ucp1 and other BAT-selective genes, implying that mitochondria… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 4 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

References

Publications referenced by this paper.
Showing 1-10 of 77 references

function and physiological significance

B Cannon, Nedergaard J. Brown adipose tissue
Physiol Rev • 2004
View 3 Excerpts
Highly Influenced

Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 2014
View 1 Excerpt

Mitohormesis

J Yun, T. Finkel
Cell Metab • 2014

Mitohormesis. Cell Metab

J Yun, T. Finkel
2014
View 1 Excerpt

Similar Papers

Loading similar papers…