Role of Endocrine , Autocrine , and Paracrine Interactions in the Development of Mammary Hyperplasia in Wnt-\ Transgenic Mice 1

The Wnt-\ proto-oncogene is transcriptionally activated by mouse mammary tumor virus in mouse mammary tumor virus-induced tumors. Previous studies using transgenic mice showed that \\'nt-\ expression in mammary gland causes alveolar hyperplasias which resemble mam mary glands of pregnant mice. To understand the role of mammogenic hormones in the genesis of… (More)