Role of E2F-1 in chemosensitivity.

  title={Role of E2F-1 in chemosensitivity.},
  author={Debabrata Banerjee and Barbara Schnieders and Jenny Z. Fu and Debasis Adhikari and S. C. Zhao and Joseph R. Bertino},
  journal={Cancer research},
  volume={58 19},
The E2F family of transcription factors, in partnership with DP proteins, is thought to regulate transcription of genes that encode protein products that are required for DNA synthesis, which include important cancer chemotherapeutic targets such as thymidylate synthase and dihydrofolate reductase. This study was conducted to investigate the effects of… CONTINUE READING