Role of Dietary Antioxidants in the Preservation of Vascular Function and the Modulation of Health and Disease

@inproceedings{Varadharaj2017RoleOD,
  title={Role of Dietary Antioxidants in the Preservation of Vascular Function and the Modulation of Health and Disease},
  author={Saradhadevi Varadharaj and Owen J Kelly and Rami N. Khayat and P. Saravanamuthu Kumar and Naseer Ahmed and Jay L. Zweier},
  booktitle={Front. Cardiovasc. Med.},
  year={2017}
}
In vascular diseases, including hypertension and atherosclerosis, vascular endothelial dysfunction (VED) occurs secondary to altered function of endothelial nitric oxide synthase (eNOS). A novel redox regulated pathway was identified through which eNOS is uncoupled due to S-glutathionylation of critical cysteine residues, resulting in superoxide free… CONTINUE READING