Role of DREF in transcriptional regulation of the Drosophila p53 gene

@article{TrongTue2010RoleOD,
  title={Role of DREF in transcriptional regulation of the Drosophila p53 gene},
  author={N Trong-Tue and Dang Thi Phuong Thao and Mitsuko Yamaguchi},
  journal={Oncogene},
  year={2010},
  volume={29},
  pages={2060-2069}
}
The tumor suppressor protein p53 has a critical role in safeguarding the integrity of the genome. Its functions are well understood but factors responsible for the transcriptional regulation of the p53 gene are almost entirely unknown. The DNA replication-related element (DRE)/DNA replication-related element-binding factor (DREF) transcriptional regulatory system is established as a master key to cell proliferation in Drosophila. DREF binds specifically to DRE sequences in the Drosophila p53… CONTINUE READING
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Identification of the Drosophila skpA gene as a novel target of the transcription factor DREF

  • DTP Thao, H Ida, H Yoshida, M. Yamaguchi
  • Exp Cell Res
  • 2006
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