Role of DJ-1 in Parkinson's disease

@article{Lev2007RoleOD,
  title={Role of DJ-1 in Parkinson's disease},
  author={Nirit Lev and Dusan Roncevich and Debby Ickowicz and Eldad Melamed and Daniel Offen},
  journal={Journal of Molecular Neuroscience},
  year={2007},
  volume={29},
  pages={215-225}
}
Parkinson's disease (PD), one of the most common neurodegenerative diseases, is a multifactorial disease caused by both genetic and environmental factors. Although most patients suffering from PD have a sporadic disease, several genetic causes have been identified in recent years, including α-synuclein, parkin, PINK1, dardarm (LRRK2), and DJ-1. DJ-1 deletions and point mutations have been found worldwide, and loss of functional protein was shown to cause autosomal recessive PD. Moreover, DJ-1… Expand
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