Role of Cyclic Adenosine 3’,5’-Monophosphate and the Cyclic Adenosine 3’, 5’-Monophosphate Receptor Protein in the Initiation of Zac Transcription


Optimal transcription of the lac operon in a defined purified in vitro system is dependent upon the concentrations of cyclic adenosine 3’,5’-monophosphate (cyclic AMP), the cyclic AMP-binding protein (CRP) and RNA polymerase. The concentration of CRP required for maximal Zac transcription varies proportionately with the concentration of lac DNA used as… (More)


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