Role of Ca(2+) mobilization in desensitization of beta-adrenoceptors by platelet-derived growth factor in airway smooth muscle.

Abstract

Platelet-derived growth factor (PDGF), which is released from eosinophils and fibroblasts, may be implicated in the pathophysiology of bronchial asthma. To examine the involvement of airway inflammation in beta-adrenergic desensitization, the present study was designed to determine whether pre-exposure to PDGF deteriorates beta-adrenoceptor function in… (More)
DOI: 10.1016/j.ejphar.2008.06.072

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Cite this paper

@article{Ikenouchi2008RoleOC, title={Role of Ca(2+) mobilization in desensitization of beta-adrenoceptors by platelet-derived growth factor in airway smooth muscle.}, author={Tadasuke Ikenouchi and Hiroaki Kume and Tetsuya Oguma and Yasushi Makino and Akira Shiraki and Yasushi Ito and Kaoru Shimokata}, journal={European journal of pharmacology}, year={2008}, volume={591 1-3}, pages={259-65} }