Role of CRF in stress-related alterations of gastric and colonic motor function.

@article{Tach1993RoleOC,
  title={Role of CRF in stress-related alterations of gastric and colonic motor function.},
  author={Yvette F. Tach{\'e} and Hubert M{\"o}nnikes and Bruno Bonaz and Jean Rivier},
  journal={Annals of the New York Academy of Sciences},
  year={1993},
  volume={697},
  pages={233-43}
}
Major advances have been made in the understanding of the pathophysiology of stress-related alteration of gut function. A wealth of information indicates that CRF is involved in the central mechanisms by which stress inhibits gastric emptying while stimulating colonic motor function. CRF acts in the PVN to trigger both the inhibition of gastric emptying and the stimulation of colonic motor function in response to stress, in addition to previously established endocrine and behavioral responses… CONTINUE READING
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